Currently: Assistant Professor, Endicott College
Grace is interested in the niche adaptation and evolution of cross-domain bacterial symbionts. While in the Barak lab, she combined proteomic data, computational modeling, and reverse genetics to characterize the metabolic requirements of the plant-associated human pathogen Salmonella enterica during plant colonization. Determining the metabolic networks that contribute to the fitness of S. enterica on plants will identify factors limiting S. enterica proliferation in this environment and reveal physiological targets for novel intervention strategies for fresh produce.
PhD. Plant Pathology. Minor: Microbiology. University of Wisconsin – Madison. 2016.
MS. Molecular Biosciences and Bioengineering. University of Hawaii at Manoa. 2010.
BS. Microbiology. University of Hawaii at Manoa. 2009.
Grace Kwan, Brett Plagenz, Kimberly Cowles, Tippapha Pisithkul, Daniel Amador-Noguez, and Jeri D. Barak. Few Differences in metabolic network use found between Salmonella enterica colonization of plants and typhoidal mice. Front. Microbiol. doi: 10.3389/fmicb.2018.00695 Link
Kwan, G., Pisithkul, T., Amador-Noguez, D., and Barak, J.D. 2015. De novo amino acid biosynthesis contributes to Salmonella enterica growth in alfalfa seedling exudates. Appl. Environ. Microbiol. Link.
Kwan, G., Charkowski, A.O., and Barak, J.D. 2013. Salmonella enterica moderates Pectobacterium carotovorum populations and virulence on lettuce. mBio. 4:e00557-12. Link